Losing 10-15% of your body weight? Only now does the weight loss start to positively affect all these information systems. And it matters!

How do I gain weight? We don't look at the plate, but at the brain. Here come the information networks, through nerves and hormones, from fat tissue, from the pancreas, from the digestive tract. The brain then regulates the balance between energy intake through food - calories - and energy expenditure.

We disrupt information networks if we're sedentary. We also disrupt it by smoking, by being stressed, by having heavy meals, especially in the evening, or by snacking all day long.

How? The appetite is regulated by the central nervous system. From three different places. I'm hungry, I eat. This is normal, physiological hunger. It's controlled by the hypothalamus.

PhD, Prof. Cătălina Poiană, primary care endocrinologist: "There are hormones that create hunger and hormones that increase satiety. The interplay of these regulates this part of eating behavior".

"I crave something good!". "I could go for pizza!". The pleasure of eating. It's regulated by another part of the brain - the mesolimbic system. The third place - the prefrontal lobe. Th executive function. I decide to eat! The decision to eat is the last in the complicated eating behavior.

The decision is yours. You have the final say regarding the plate. But why do I need to go to the doctor to lose weight?

The doctor sets your diet. So that you lose 10-15% of your body weight. Only now does the weight loss start to positively affect all these information systems in the body. Then comes another complicated process. Adaptation.

PhD, Prof. Cătălina Poiană, primary care endocrinologist: "After losing weight, the body develops an adaptive mechanism to this loss - it reduces energy consumption, so you still end up in imbalance. Within this adaptive mechanism, there are imbalances between the hormones in the hypothalamus. Some increase appetite, others signal satiety. Hormones that increase hunger are exacerbated, and those that signal satiety are reduced, all as an adaptation to weight loss. After weight loss, the body struggles to adapt, and then you regain weight or weight loss becomes impossible".

This is because the feeling of hunger will be significant, and the feeling of satiety appears more slowly. Because of the hormones produced by the hypothalamus, which adapt to the new weight.

We look at the level of fat cells, adipocytes. And here we find intelligence.

Anca Sima, PhD Academician, Institute of Cellular Biopathology: "Once you've accumulated fat tissue, you can shrink it back through dieting; it decreases. However, pre-adipocytes retain a strong memory of this process, and at the first chance, without repeating past actions, they begin to proliferate. These cells have a memory".

And because of memory, after we've lost weight once, we subsequently gain weight faster. Obesity is a disease. And it's treated by a doctor. Even the diet is adapted by the doctor. It's up to you to follow it.